Tumor banks have played pivotal roles in the development of diagnostic tools and therapeutic reagents, including Her-2/neu (amplified in breast cancers), prostate specific antigen (PSA test), CA125 antigen test for ovarian cancers, Herceptin (antibody therapy targeted to Her-2/neu in treatment of breast cancers) and Rituximab (monoclonal antibody to CD20) for treatment of B cell malignancies.
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